Cystic (fluid filled) lesions of the pancreas are increasingly being identified with advancements in imaging technologies. The majority of cystic lesions are benign and won’t trouble you but as with all pancreatic lesions it is important that appropriate assessment of the lesion is undertaken. Cancerous lesions can appear cystic and some cystic lesions are known to harbour pre-cancerous tissue. Simple cysts, serous cysts, mucinous cysts and intra-ductal papillary mucinous neoplasms (or IPMN) are all examples. Blood tests and dedicated scans will help narrow the diagnostic possibilities and assist with regard to decision making. Often invasive tests (eg. endoscopic ultrasound) may be required to fully investigate the lesion. Surgery may be required for lesions that are “high risk” for cancer or where diagnostic doubt remains. Your ANZHPBA aligned surgeon will be able to help you understand the specific problem and tailor a management approach to your individual situation.