Cushing’s syndrome

Cushing’s syndrome involves the inappropriate and excessive secretion of cortisol from the adrenal gland. This is usually a result of a benign tumour, called an adenoma that arises within the specific adrenal gland tissue that produces cortisol. Cortisol is an important hormone that helps your body deal with stress and is fundamental to good health. When produced in excess however, cortisol can lead to numerous problems. Weight gain, skin changes, altered mood, poor bone health and elevated blood pressure can all be manifestations. Long term exposure to excessive amounts of circulating cortisol can be extremely deleterious and should be corrected.

Referral for consideration of investigation and/or management of Cushing’s Syndrome should be the next step. You ANZES recognised endocrine surgeon will be able to talk you through the necessary steps toward confirming a diagnosis and necessary management. This will generally entail additional blood, urine and imaging tests. Additional discussions between your surgeon and the multidisciplinary management team may also be required to assist in confirmation of the diagnosis and to formulate a management plan.

In general, surgical removal of the cortisol producing tumour (adrenalectomy) is the only way to cure the problem. Experience tells us that this is usually the single most useful way of managing the problem and will ensure that your long-term health is optimised. Your ANZES recognised endocrine surgeon will be able to assist you in making these decisions about your health.