Conn’s syndrome (otherwise known as primary aldosteronism) involves the inappropriate and excessive secretion of aldosterone from the adrenal gland. This is usually a result of a benign tumour, called an adenoma that arises within the specific adrenal gland tissue that produces aldosterone. In health, aldosterone is an important hormone that helps your body regulate salt and water balance, primarily through its effect on the kidneys and blood vessels. When produced in excess however, the way in which the kidney manages electrolyte and water balance changes. Sodium and associated water retention occur and in addition to a direct effect on the blood vessels, patients generally develop high blood pressure. Understandably, the diagnosis of Conn’s Syndrome often isn’t considered initially, as high blood pressure is relatively common. However, if you end up having to take multiple different medications to control your blood pressure, secondary causes should be considered.
Referral for consideration of investigation and/or management of Conn’s Syndrome should be the next step. You ANZES recognised endocrine surgeon will be able to talk you through the necessary steps toward confirming a diagnosis and necessary management. This will generally entail additional blood, urine and imaging tests. Additional discussions between your surgeon and the multidisciplinary management team may also be required to assist in confirmation of the diagnosis and to formulate a range of management options.
In general, surgical removal of the aldosterone producing tumour (adrenalectomy) is the only way to cure the problem. Experience tells us that this is usually the single most useful way of managing the problem and will ensure that blood pressure is easier to manage longer term. Your ANZES recognised endocrine surgeon will be able to assist you in making these decisions about your health.
